As museums have acknowledged their legacy as colonial institutions, many have reimagined their mission as agents of decolonization and social justice. The pandemic disruption, the Black Lives Matter movement, and other community issues are driving still more rapid and drastic changes and providing opportunities for reflection and growth. How can American museums—especially those that have strong relationships with Indigenous communities—respond to current national conditions of social unrest and political turmoil? How have New England museums fared and what is likely to happen over the next two to three years? Speakers in this January 4, 2021 Zoom video include Chris Newell (Passamaquoddy), Executive Director and Senior Partner to Wabanaki Nations, Abbe Museum; Jane Pickering, William & Muriel Seabury Howells Director, Peabody Museum of Archaeology & Ethnology, Harvard University; Lorén Spears (Narragansett), Executive Director, Tomaquag Museum; and Moderated by Castle McLaughlin, Museum Curator of North American Ethnography, Peabody Museum of Archaeology & Ethnology, Harvard University